Exploring Perinatal Asphyxia by Metabolomics
نویسندگان
چکیده
منابع مشابه
Perinatal asphyxia: a review from a metabolomics perspective.
Perinatal asphyxia is defined as an oxygen deprivation that occurs around the time of birth, and may be caused by several perinatal events. This medical condition affects some four million neonates worldwide per year, causing the death of one million subjects. In most cases, infants successfully recover from hypoxia episodes; however, some patients may develop HIE, leading to permanent neurolog...
متن کاملNeurological Complications of Perinatal Asphyxia
The degree of asphyxia is best ascertained by measuring the amount of fetal acidosis determined by umbilical arterial blood. An umbilical arterial pH of less than 7.0 is seen in about 0.3% of deliveries.1 It indicates a severity of acidosis that places the fetus at risk for permanent neurological damage because of asphyxia. However, the outcome of infants with umbilical cord pH of less than 7.0...
متن کاملChromosomal aberrations in Perinatal Asphyxia
This study was conducted to evaluate the level of chromosomal damage in perinatal asphyxia and correlate it with severity of asphyxia. Fourty term neonates with asphyxia and twenty term babies without asphyxia were included in this case control study. Blood samples were collected within 24 hours of birth for karyotyping and oxidative stress by serum malondealdehyde (MDA) estimation. The degree ...
متن کاملNeuroprotective treatment for perinatal asphyxia.
BACKGROUND Perinatal asphyxia can cause serious illness or death. By taking steps in the «latent phase», which occurs 6-24 hours after the hypoxic event, the neurological damage caused by perinatal asphyxia can be limited. We wish to present a selection of such measures that are either established treatment today or that appear promising. METHOD We searched in the Medline and Cochrane Library...
متن کاملTherapeutic hypothermia following perinatal asphyxia.
Well constructed and carefully analysed trials of hypothermic neural rescue therapy for infants with neonatal encephalopathy have recently been reported. The data suggest that either selective head cooling or total body cooling reduces the combined chance of death or disability after birth asphyxia. However, as there are still unanswered questions about these treatments, many may still feel tha...
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ژورنال
عنوان ژورنال: Metabolites
سال: 2020
ISSN: 2218-1989
DOI: 10.3390/metabo10040141